Urotensin Receptor

UT receptor

Urotensin Receptor

Related Products

Urotensin receptor (UT) is a G-protein coupled receptor which binds the peptide hormoneurotensin. The urotensin-II (UT) receptor is a Gq/11-protein-coupled receptor that mediates complex hemodynamic effects and influences neuromuscular physiology. The UT receptor displays greatest expression levels in the peripheral vasculature, heart and kidney, although they are found elsewhere, notably the central nervous system, at lower levels. The UT receptor produces potent but variable vasoconstrictor effects in some vascular beds, yet mediates vasodilation in others; it has also been implicated in osmoregulation.

Urotensin Receptor Related Products (27):

By Effects:	Inhibitors (2) Agonists (5) Antagonists (14) Activators (3)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-P1166

UFP-803	Antagonist
UFP-803 is a potent urotensin-II receptor (UT) ligand. UFP-803 has lower residual agonist activity, so it may be an important tool for the investigations on the role played by the UT system in physiology and pathology.

HY-P1167

[Orn5]-URP	Antagonist
[Orn5]-URP is a potent and selective pure antagonist of Urotensin-II receptor (UT), with an pEC₅₀ of 7.24. [Orn5]-URP displays no agonist activity.

HY-P1166A

UFP-803 TFA	Antagonist
UFP-803 TFA is a potent urotensin-II receptor (UT) ligand. UFP-803 TFA has lower residual agonist activity, so it may be an important tool for the investigations on the role played by the UT system in physiology and pathology.

HY-P3957

Urotensin II, teleost fish	Agonist
Urotensin II, teleost fish is a cyclic peptide. It can be isolated from the caudal neurosecretory system of teleost fish.

HY-P1168

[Orn8]-Urotensin II (human)	Agonist
[Orn8]-Urotensin II (human), a peptide analog of urotensin II, is a UT receptor agonist. [Orn8]-Urotensin II (human) increases intracellular calcium levels in HEK293.

HY-10658

AC-7954
AC-7954 is a selective nonpeptidic urotensin receptor agonist (EC₅₀: 300 nM at the human UII receptor).

HY-19924

GSK-1440115	Antagonist
GSK-1440115 is an antagonist of the Urotensin II Receptor with an IC₅₀ value of 82.3 nM.

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